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The database has 60243Ki values for searching, and is growing
This list shows the Top 100 Receptors/Targets in Ki
Please let us know if you feel we should add any papers or data. We welcome all feedback/suggestions/comments
Other features on Ki DB are: Download Ki, Data Mining, CDD Interface allows mining Ki database by structure, substructure or structure similarity.
Anatomical profiling of GPCR expression is offered for selected targets.

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Your search returned 37 results:

IDReceptor/AliasesUniGeneAnat. ProfilingTest Ligand Name/AliasesNCIKi (nM)PubChemChEMBLHot Ligand/AliasesSpeciesSourceReference
34022 5-HT Transporter  Aliases NCBI - UniGene N/A mirtazepine  Aliases N/A 7,943.282347 PubChem-Compound N/A 3H-5HT  Aliases RAT STRIATUM De Boer TH, et al., 1988
 
45610 5-HT Transporter  Aliases NCBI - UniGene N/A mirtazepine  Aliases N/A > 10,000.000000 PubChem-Compound N/A 3H-IMIPRAMINE  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
32724 5-HT Transporter  Aliases NCBI - UniGene N/A mirtazepine  Aliases N/A 100.000000 PubChem-Compound N/A UNDEFINED  Aliases RAT BRAIN Wikstrom HV, et al., 2002
 
28941 5-HT-S2  Aliases N/A N/A mirtazepine  Aliases N/A 8.912509 PubChem-Compound N/A 3H-MIANSERIN  Aliases RAT FR. CORTEX De Boer TH, et al., 1988
 
32713 5-HT1A  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 18.000000 PubChem-Compound N/A 3H-5CT  Aliases HUMAN CLONED Wikstrom HV, et al., 2002
 
36628 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 69.000000 PubChem-Compound N/A 125I-R091150  Aliases HUMAN CLONED Fernandez J, et al., 2005
 
32715 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 2.000000 PubChem-Compound N/A 3H-KETANSERIN  Aliases RAT CORTEX Wikstrom HV, et al., 2002
 
36642 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 39.000000 PubChem-Compound N/A 3H-MESULERGINE  Aliases HUMAN CLONED Fernandez J, et al., 2005
58980 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 8.900000 PubChem-Compound N/A 3H-MESULERGINE  Aliases HUMAN CLONED Roth B. et al., 2006
Average23.95 
32748 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 5.500000 PubChem-Compound N/A 3H-MESULERGINE  Aliases RAT CLONED Wikstrom HV, et al., 2002
 
36635 5-HT7  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 265.000000 PubChem-Compound N/A 3H-5HT  Aliases HUMAN CLONED Fernandez J, et al., 2005
 
36663 adrenergic Alpha1  Aliases N/A N/A mirtazepine  Aliases N/A 608.000000 PubChem-Compound N/A 3H-PRAZOSIN  Aliases RAT CLONED Fernandez J, et al., 2005
 
32718 adrenergic Alpha1  Aliases N/A N/A mirtazepine  Aliases N/A 1,050.000000 PubChem-Compound N/A 3H-PRAZOSIN  Aliases RAT BRAIN Wikstrom HV, et al., 2002
 
28929 adrenergic Alpha1  Aliases N/A N/A mirtazepine  Aliases N/A 371.535229 PubChem-Compound N/A 3H-PRAZOSIN  Aliases RAT FR. CORTEX De Boer TH, et al., 1988
 
58979 adrenergic Alpha1A  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 371.000000 PubChem-Compound N/A 3H-PRAZOSIN  Aliases HUMAN CLONED Roth B. et al., 2006
 
33848 adrenergic Alpha2  Aliases N/A N/A mirtazepine  Aliases N/A 58.000000 PubChem-Compound N/A 3H-IDAZOXAN  Aliases RAT CORTEX Wikstrom HV, et al., 2002
 
28935 adrenergic Alpha2  Aliases N/A N/A mirtazepine  Aliases N/A 112.201845 PubChem-Compound N/A 3H-RAUWOLSCINE  Aliases RAT FR. CORTEX De Boer TH, et al., 1988
 
36670 adrenergic Alpha2A  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 20.000000 PubChem-Compound N/A 3H-RAUWOLSCINE  Aliases HUMAN CLONED Fernandez J, et al., 2005
 
36677 adrenergic Alpha2C  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 18.000000 PubChem-Compound N/A 3H-RAUWOLSCINE  Aliases HUMAN CLONED Fernandez J, et al., 2005
 
28957 Cholinergic, muscarinic  Aliases N/A N/A mirtazepine  Aliases N/A 794.328235 PubChem-Compound N/A 3H-QNB  Aliases RAT WHOLE BRAIN De Boer TH, et al., 1988
 
36607 DOPAMINE D1  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 4,167.000000 PubChem-Compound N/A 3H-SCH23390  Aliases HUMAN CLONED Fernandez J, et al., 2005
 
36614 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 5,454.000000 PubChem-Compound N/A 3H-SPIPERONE  Aliases HUMAN CLONED Fernandez J, et al., 2005
 
28947 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 3,981.071706 PubChem-Compound N/A 3H-SPIPERONE  Aliases RAT STRIATUM De Boer TH, et al., 1988
 
32709 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 1,460.000000 PubChem-Compound N/A 3H-SPIPERONE  Aliases RAT Corpus Striatum Wikstrom HV, et al., 2002
 
36621 DOPAMINE D3  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 5,723.000000 PubChem-Compound N/A 125I-IODOSULPRIDE  Aliases HUMAN CLONED Fernandez J, et al., 2005
 
32710 DOPAMINE D3  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 20.000000 PubChem-Compound N/A 3H-SPIPERONE  Aliases HUMAN CLONED Wikstrom HV, et al., 2002
 
32711 DOPAMINE D4.2  Aliases N/A N/A mirtazepine  Aliases N/A 25.000000 PubChem-Compound N/A 3H-YM 09151-2  Aliases HUMAN CLONED Wikstrom HV, et al., 2002
 
34015 Dopamine Transporter  Aliases NCBI - UniGene N/A mirtazepine  Aliases N/A > 10,000.000000 PubChem-Compound N/A 3H-dopamine  Aliases RAT STRIATUM De Boer TH, et al., 1988
 
45612 Dopamine Transporter  Aliases NCBI - UniGene N/A mirtazepine  Aliases N/A > 10,000.000000 PubChem-Compound N/A 3H-WIN 35,428  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
28951 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 0.501187 PubChem-Compound N/A 3H-MEPYRAMINE  Aliases RAT WHOLE BRAIN De Boer TH, et al., 1988
 
36656 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 1.600000 PubChem-Compound N/A 3H-PYRILAMINE  Aliases HUMAN CLONED Fernandez J, et al., 2005
58978 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 0.500000 PubChem-Compound N/A 3H-PYRILAMINE  Aliases HUMAN CLONED Roth B. et al., 2006
Average1.05 
32720 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling mirtazepine  Aliases N/A 5.100000 PubChem-Compound N/A 3H-PYRILAMINE  Aliases GUINEA PIG LUNG Wikstrom HV, et al., 2002
 
45611 Norepinephrine transporter  Aliases N/A N/A mirtazepine  Aliases N/A 4,600.000000 PubChem-Compound N/A 3H-Nisoxetine  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
36649 Norepinephrine transporter  Aliases N/A N/A mirtazepine  Aliases N/A 1,640.000000 PubChem-Compound N/A 3H-Nisoxetine  Aliases RAT CLONED Fernandez J, et al., 2005
 
34006 Norepinephrine transporter  Aliases N/A N/A mirtazepine  Aliases N/A 2,511.886432 PubChem-Compound N/A 3H-Noradrenaline  Aliases RAT STRIATUM De Boer TH, et al., 1988
 
32722 Norepinephrine transporter  Aliases N/A N/A mirtazepine  Aliases N/A 260.000000 PubChem-Compound N/A UNDEFINED  Aliases RAT BRAIN Wikstrom HV, et al., 2002
 


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