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The database has 60243Ki values for searching, and is growing
This list shows the Top 100 Receptors/Targets in Ki
Please let us know if you feel we should add any papers or data. We welcome all feedback/suggestions/comments
Other features on Ki DB are: Download Ki, Data Mining, CDD Interface allows mining Ki database by structure, substructure or structure similarity.
Anatomical profiling of GPCR expression is offered for selected targets.

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Your search returned 43 results:

IDReceptor/AliasesUniGeneAnat. ProfilingTest Ligand Name/AliasesNCIKi (nM)PubChemChEMBLHot Ligand/AliasesSpeciesSourceReference
45468 5-HT Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 317.000000 PubChem-Compound N/A 3H-5-HT Uptake  Aliases HUMAN CLONED Vaishnavi SN, et al., 2004
 
9664 5-HT Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 279.000000 PubChem-Compound N/A 3H-5HT  Aliases HUMAN CLONED Owens MJ, et al, 1997
 
35073 5-HT Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 1,700.000000 PubChem-Compound N/A 3H-5HT  Aliases RAT Corpus Striatum Koe BK et al., 1983
 
9537 5-HT Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 15.000000 PubChem-Compound N/A 3H-CITALOPRAM  Aliases HUMAN CLONED Owens MJ, et al, 1997
45450 5-HT Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 18.000000 PubChem-Compound N/A 3H-CITALOPRAM  Aliases HUMAN CLONED Vaishnavi SN, et al., 2004
Average16.50 
9646 5-HT Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 60.000000 PubChem-Compound N/A 3H-CITALOPRAM  Aliases RAT CORTEX Owens MJ, et al, 1997
 
4471 5-HT Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 60.800000 PubChem-Compound N/A 3H-IMIPRAMINE  Aliases RAT BRAIN PALVIMAKI EP, ET AL., 1996
 
47714 5-HT Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 197.000000 PubChem-Compound N/A 3H-5-HT Uptake  Aliases RAT FR. CORTEX Cheetham SC, et.al., 1993
 
45628 5-HT Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 18.000000 PubChem-Compound N/A 3H-IMIPRAMINE  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
47692 5-HT Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 60.800000 PubChem-Compound N/A 3H-PAROXETINE  Aliases RAT FR. CORTEX Cheetham SC, et.al., 1993
 
11625 5-HT1A  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 294.000000 PubChem-Compound N/A 3H-8-OH-DPAT  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
11644 5-HT2  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 41.000000 PubChem-Compound N/A 3H-KETANSERIN  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
4453 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 5.000000 PubChem-Compound N/A 3H-KETANSERIN  Aliases RAT CLONED PALVIMAKI EP, ET AL., 1996
 
4435 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 8.500000 PubChem-Compound N/A 3H-MESULERGINE  Aliases RAT CLONED PALVIMAKI EP, ET AL., 1996
 
4211 5-HT6  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 148.000000 PubChem-Compound N/A 125I-LSD  Aliases RAT CLONED MONSMA FJ Jr. ET AL., 1993
6587 5-HT6  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 148.000000 PubChem-Compound N/A 125I-LSD  Aliases RAT CLONED SEBBEN M, ET AL., 1994
15788 5-HT6  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 147.910000 PubChem-Compound N/A 125I-LSD  Aliases RAT CLONED BOESS FG, ET AL., 1994
Average147.97 
11587 adrenergic Alpha1  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 55.000000 PubChem-Compound N/A 3H-PRAZOSIN  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
11606 adrenergic Alpha2  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 2,030.000000 PubChem-Compound N/A 3H-RAUWOLSCINE  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
13277 adrenergic Beta  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A > 10,000.000000 PubChem-Compound N/A 3H-DHA  Aliases Mammalian BRAIN Bylund DB, et al., 1976
 
11568 Cholinergic, muscarinic  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 37.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
41999 Cholinergic, muscarinic M1  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 40.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42018 Cholinergic, muscarinic M2  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 110.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42037 Cholinergic, muscarinic M3  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 50.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42056 Cholinergic, muscarinic M4  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 84.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42075 Cholinergic, muscarinic M5  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 97.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
11662 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 2,570.000000 PubChem-Compound N/A 3H-SPIPERONE  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
45462 Dopamine Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 1,200.000000 PubChem-Compound N/A 125I-RTI-55 Binding  Aliases HUMAN CLONED Vaishnavi SN, et al., 2004
 
45480 Dopamine Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 5,000.000000 PubChem-Compound N/A 3H-dopamine  Aliases HUMAN CLONED Vaishnavi SN, et al., 2004
 
35084 Dopamine Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A > 10,000.000000 PubChem-Compound N/A 3H-dopamine  Aliases RAT Corpus Striatum Koe BK et al., 1983
 
45630 Dopamine Transporter  Aliases NCBI - UniGene N/A NORTRYPTYLINE  Aliases N/A 1,140.000000 PubChem-Compound N/A 3H-WIN 35,428  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
12003 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 8.400000 PubChem-Compound N/A 3H-doxepin  Aliases HUMAN CORTICAL MEMBRANES Kanba S, et al., 1984
 
47197 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 15.100000 PubChem-Compound N/A 3H-MEPYRAMINE  Aliases HUMAN CLONED Ghoneim OM, et al., 2006
 
13043 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 46.000000 PubChem-Compound N/A 3H-MEPYRAMINE  Aliases RAT BRAIN Tran VT, et al., 1978
 
11548 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling NORTRYPTYLINE  Aliases N/A 6.300000 PubChem-Compound N/A 3H-PYRILAMINE  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
45474 Norepinephrine transporter  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 8.300000 PubChem-Compound N/A 3H-NE Uptake  Aliases HUMAN CLONED Vaishnavi SN, et al., 2004
 
9628 Norepinephrine transporter  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 1.800000 PubChem-Compound N/A 3H-Nisoxetine  Aliases HUMAN CLONED Owens MJ, et al, 1997
45456 Norepinephrine transporter  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 1.490000 PubChem-Compound N/A 3H-Nisoxetine  Aliases HUMAN CLONED Vaishnavi SN, et al., 2004
Average1.65 
9684 Norepinephrine transporter  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 0.990000 PubChem-Compound N/A 3H-Nisoxetine  Aliases RAT CORTEX Owens MJ, et al, 1997
 
9703 Norepinephrine transporter  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 21.000000 PubChem-Compound N/A 3H-Norepinephrine  Aliases HUMAN CLONED Owens MJ, et al, 1997
 
35095 Norepinephrine transporter  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 25.000000 PubChem-Compound N/A 3H-Norepinephrine  Aliases RAT HYPOTHALAMUS Koe BK et al., 1983
 
45629 Norepinephrine transporter  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 4.370000 PubChem-Compound N/A 3H-Nisoxetine  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
32686 Sigma  Aliases N/A N/A NORTRYPTYLINE  Aliases N/A 2,000.000000 PubChem-Compound N/A 3H-Tol2Gdn  Aliases GUINEA PIG BRAIN Weber E, et al., 1986
 


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