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The database has 60243Ki values for searching, and is growing
This list shows the Top 100 Receptors/Targets in Ki
Please let us know if you feel we should add any papers or data. We welcome all feedback/suggestions/comments
Other features on Ki DB are: Download Ki, Data Mining, CDD Interface allows mining Ki database by structure, substructure or structure similarity.
Anatomical profiling of GPCR expression is offered for selected targets.

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Your search returned 36 results:

IDReceptor/AliasesUniGeneAnat. ProfilingTest Ligand Name/AliasesNCIKi (nM)PubChemChEMBLHot Ligand/AliasesSpeciesSourceReference
47718 5-HT Transporter  Aliases NCBI - UniGene N/A AMOXAPINE  Aliases N/A 409.000000 PubChem-Compound ChEMBL 3H-5-HT Uptake  Aliases RAT FR. CORTEX Cheetham SC, et.al., 1993
 
45550 5-HT Transporter  Aliases NCBI - UniGene N/A AMOXAPINE  Aliases N/A 58.000000 PubChem-Compound ChEMBL 3H-IMIPRAMINE  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
4465 5-HT Transporter  Aliases NCBI - UniGene N/A AMOXAPINE  Aliases N/A 290.000000 PubChem-Compound ChEMBL 3H-IMIPRAMINE  Aliases RAT BRAIN PALVIMAKI EP, ET AL., 1996
 
47696 5-HT Transporter  Aliases NCBI - UniGene N/A AMOXAPINE  Aliases N/A 290.000000 PubChem-Compound ChEMBL 3H-PAROXETINE  Aliases RAT FR. CORTEX Cheetham SC, et.al., 1993
 
10714 5-HT2  Aliases N/A N/A AMOXAPINE  Aliases N/A 1.000000 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED ROTH ET AL., 1993
 
4447 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 1.000000 PubChem-Compound ChEMBL 3H-KETANSERIN  Aliases RAT CLONED PALVIMAKI EP, ET AL., 1996
 
4536 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 1.300000 PubChem-Compound ChEMBL 3H-SPIPERONE  Aliases RAT BRAIN ROTH BL, ET AL., 1995
 
19801 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 0.500000 PubChem-Compound ChEMBL UNDEFINED  Aliases HUMAN CLONED Seeman P, Tallerico T., 1998
 
10732 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 1.990000 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED ROTH ET AL., 1993
 
4429 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 2.000000 PubChem-Compound ChEMBL 3H-MESULERGINE  Aliases RAT CLONED PALVIMAKI EP, ET AL., 1996
 
4198 5-HT6  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 30.400000 PubChem-Compound ChEMBL 125I-LSD  Aliases RAT CLONED MONSMA FJ Jr. ET AL., 1993
6589 5-HT6  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 30.400000 PubChem-Compound ChEMBL 125I-LSD  Aliases RAT CLONED SEBBEN M, ET AL., 1994
Average30.40 
4344 5-HT6  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 50.000000 PubChem-Compound ChEMBL 3H-LSD  Aliases HUMAN CLONED KOHEN R, ET AL., 1996
 
3115 5-HT6  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 6.000000 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED ROTH ET AL., 1993
40296 5-HT6  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 6.309573 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED Glusa E, et al., 2000
Average6.15 
6338 5-HT7  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 1,412.530000 PubChem-Compound ChEMBL 3H-5CT  Aliases GUINEA PIG CORTEX TO ZP, ET AL., 1995
 
6302 5-HT7  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 186.200000 PubChem-Compound ChEMBL 3H-5CT  Aliases GUINEA PIG CLONED TO ZP, ET AL., 1995
 
3155 5-HT7  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 40.600000 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED ROTH ET AL., 1993
40312 5-HT7  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 39.810717 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED Glusa E, et al., 2000
Average40.21 
62808 Alpha 1 Adrenergic Receptor  Aliases N/A N/A AMOXAPINE  Aliases N/A 50.000000 PubChem-Compound ChEMBL 3H-PRAZOSIN  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
62837 Alpha 2 Adrenergic Receptor  Aliases N/A N/A AMOXAPINE  Aliases N/A 2,600.000000 PubChem-Compound ChEMBL 3H-RAUWOLSCINE  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
62856 D2  Aliases N/A N/A AMOXAPINE  Aliases N/A 160.000000 PubChem-Compound ChEMBL 3H-SPIROPERIDOL  Aliases HUMAN Brain caudate nucleus Richelson, Elliott et. al, 1984
 
4500 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 20.000000 PubChem-Compound ChEMBL 3H-SPIPERONE  Aliases RAT BRAIN ROTH BL, ET AL., 1995
 
39013 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 38.000000 PubChem-Compound ChEMBL R-SAT  Aliases HUMAN CLONED Burstein ES, et al., 2005
39044 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 3.600000 PubChem-Compound ChEMBL R-SAT  Aliases HUMAN CLONED Burstein ES, et al., 2005
Average20.80 
19775 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 16.000000 PubChem-Compound ChEMBL UNDEFINED  Aliases HUMAN CLONED Seeman P, Tallerico T., 1998
 
39085 DOPAMINE D3  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 31.000000 PubChem-Compound ChEMBL R-SAT  Aliases HUMAN CLONED Burstein ES, et al., 2005
39114 DOPAMINE D3  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 11.000000 PubChem-Compound ChEMBL R-SAT  Aliases HUMAN CLONED Burstein ES, et al., 2005
Average21.00 
4499 DOPAMINE D4  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 92.000000 PubChem-Compound ChEMBL 3H-SPIPERONE  Aliases RAT CLONED ROTH BL, ET AL., 1995
 
39155 DOPAMINE D4  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 40.000000 PubChem-Compound ChEMBL R-SAT  Aliases HUMAN CLONED Burstein ES, et al., 2005
 
19838 DOPAMINE D4  Aliases NCBI - UniGene Anatomical Profiling AMOXAPINE  Aliases N/A 2.000000 PubChem-Compound ChEMBL UNDEFINED  Aliases HUMAN CLONED Seeman P, Tallerico T., 1998
 
45552 Dopamine Transporter  Aliases NCBI - UniGene N/A AMOXAPINE  Aliases N/A 4,310.000000 PubChem-Compound ChEMBL 3H-WIN 35,428  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
62759 H1  Aliases N/A N/A AMOXAPINE  Aliases N/A 25.000000 PubChem-Compound ChEMBL 3H-doxepin  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
62787 Muscarinic Acetylcholine Receptor  Aliases N/A N/A AMOXAPINE  Aliases N/A 1,000.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN Brain caudate nucleus Richelson, Elliott et. al, 1984
 
45551 Norepinephrine transporter  Aliases N/A N/A AMOXAPINE  Aliases N/A 16.000000 PubChem-Compound ChEMBL 3H-Nisoxetine  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
26281 Vasopressin V3  Aliases N/A N/A AMOXAPINE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-VASOPRESSIN  Aliases HUMAN CLONED PDSP certified data
 


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