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The database has 60243Ki values for searching, and is growing
This list shows the Top 100 Receptors/Targets in Ki
Please let us know if you feel we should add any papers or data. We welcome all feedback/suggestions/comments
Other features on Ki DB are: Download Ki, Data Mining, CDD Interface allows mining Ki database by structure, substructure or structure similarity.
Anatomical profiling of GPCR expression is offered for selected targets.

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Your search returned 40 results:

IDReceptor/AliasesUniGeneAnat. ProfilingTest Ligand Name/AliasesNCIKi (nM)PubChemChEMBLHot Ligand/AliasesSpeciesSourceReference
47703 5-HT Transporter  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 5.800000 PubChem-Compound ChEMBL 3H-5-HT Uptake  Aliases RAT FR. CORTEX Cheetham SC, et.al., 1993
 
45562 5-HT Transporter  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 0.280000 PubChem-Compound ChEMBL 3H-IMIPRAMINE  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
4466 5-HT Transporter  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 0.140000 PubChem-Compound ChEMBL 3H-IMIPRAMINE  Aliases RAT BRAIN PALVIMAKI EP, ET AL., 1996
 
16773 5-HT Transporter  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 0.140000 PubChem-Compound ChEMBL 3H-PAROXETINE  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
16768 5-HT Transporter  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 1.200000 PubChem-Compound ChEMBL 3H-PAROXETINE  Aliases RAT FR. CORTEX Millan MJ, et al., 2001
47683 5-HT Transporter  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 0.140000 PubChem-Compound ChEMBL 3H-PAROXETINE  Aliases RAT FR. CORTEX Cheetham SC, et.al., 1993
Average0.67 
3340 5-HT1A  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 > 10,000.000000 PubChem-Compound ChEMBL 3H-8-OH-DPAT  Aliases HUMAN CLONED TOLL L, et. al., 1998
16798 5-HT1A  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 > 10,000.000000 PubChem-Compound ChEMBL 3H-8-OH-DPAT  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
16804 5-HT1B  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 > 10,000.000000 PubChem-Compound ChEMBL 3H-GR-125743  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
16809 5-HT1D  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 > 10,000.000000 PubChem-Compound ChEMBL 3H-GR-125743  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
16815 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 35.500000 PubChem-Compound ChEMBL 3H-KETANSERIN  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
3492 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 11.000000 PubChem-Compound ChEMBL 3H-KETANSERIN  Aliases RAT CLONED TOLL L, et. al., 1998
4448 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 15.000000 PubChem-Compound ChEMBL 3H-KETANSERIN  Aliases RAT CLONED PALVIMAKI EP, ET AL., 1996
Average13.00 
16820 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 64.600000 PubChem-Compound ChEMBL 3H-MESULERGINE  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
3550 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 52.000000 PubChem-Compound ChEMBL 3H-MESULERGINE  Aliases RAT CLONED TOLL L, et. al., 1998
4430 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 22.000000 PubChem-Compound ChEMBL 3H-MESULERGINE  Aliases RAT CLONED PALVIMAKI EP, ET AL., 1996
Average37.00 
16825 5-HT3  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 85.100000 PubChem-Compound ChEMBL 3H-BRL 43694  Aliases MOUSE CLONED Millan MJ, et al., 2001
 
3609 5-HT3  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 985.000000 PubChem-Compound ChEMBL 3H-GR-65630  Aliases MOUSE NG108-15 TOLL L, et. al., 1998
 
4203 5-HT6  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 53.800000 PubChem-Compound ChEMBL 125I-LSD  Aliases RAT CLONED MONSMA FJ Jr. ET AL., 1993
 
5253 5-HT7  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 127.000000 PubChem-Compound ChEMBL 3H-5HT  Aliases RAT CLONED RUAT M, ET AL., 1993
 
16830 adrenergic Alpha1  Aliases N/A N/A CLOMIPRAMINE  Aliases 169865 15.500000 PubChem-Compound ChEMBL 3H-PRAZOSIN  Aliases RAT FR. CORTEX Millan MJ, et al., 2001
 
16835 adrenergic Alpha1A  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 3.200000 PubChem-Compound ChEMBL 3H-PRAZOSIN  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
16840 adrenergic Alpha2  Aliases N/A N/A CLOMIPRAMINE  Aliases 169865 > 10,000.000000 PubChem-Compound ChEMBL 3H-RX821002  Aliases RAT CORTEX Millan MJ, et al., 2001
 
16845 adrenergic Alpha2A  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 525.000000 PubChem-Compound ChEMBL 3H-RX821002  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
62807 Alpha 1 Adrenergic Receptor  Aliases N/A N/A CLOMIPRAMINE  Aliases 169865 38.000000 PubChem-Compound ChEMBL 3H-PRAZOSIN  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
62838 Alpha 2 Adrenergic Receptor  Aliases N/A N/A CLOMIPRAMINE  Aliases 169865 3,200.000000 PubChem-Compound ChEMBL 3H-RAUWOLSCINE  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
62858 D2  Aliases N/A N/A CLOMIPRAMINE  Aliases 169865 190.000000 PubChem-Compound ChEMBL 3H-SPIROPERIDOL  Aliases HUMAN Brain caudate nucleus Richelson, Elliott et. al, 1984
 
3188 DOPAMINE D1  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 219.000000 PubChem-Compound ChEMBL 3H-SCH23390  Aliases HUMAN CLONED TOLL L, et. al., 1998
 
16850 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 77.600000 PubChem-Compound ChEMBL 3H-SPIPERONE  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
3248 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 162.000000 PubChem-Compound ChEMBL 3H-YM 09151-2  Aliases HUMAN CLONED TOLL L, et. al., 1998
 
16855 DOPAMINE D3  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 50.100000 PubChem-Compound ChEMBL 3H-SPIPERONE  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
3307 DOPAMINE D3  Aliases NCBI - UniGene Anatomical Profiling CLOMIPRAMINE  Aliases 169865 30.000000 PubChem-Compound ChEMBL 3H-YM 09151-2  Aliases HUMAN CLONED TOLL L, et. al., 1998
 
16794 Dopamine Transporter  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 3,020.000000 PubChem-Compound ChEMBL 3H-GBR 12935  Aliases HUMAN CLONED Millan MJ, et al., 2001
 
16788 Dopamine Transporter  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 1,230.000000 PubChem-Compound ChEMBL 3H-GBR 12935  Aliases RAT STRIATUM Millan MJ, et al., 2001
 
45564 Dopamine Transporter  Aliases NCBI - UniGene N/A CLOMIPRAMINE  Aliases 169865 2,190.000000 PubChem-Compound ChEMBL 3H-WIN 35,428  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
62761 H1  Aliases N/A N/A CLOMIPRAMINE  Aliases 169865 31.000000 PubChem-Compound ChEMBL 3H-doxepin  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
62779 Muscarinic Acetylcholine Receptor  Aliases N/A N/A CLOMIPRAMINE  Aliases 169865 37.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN Brain caudate nucleus Richelson, Elliott et. al, 1984
 
16783 Norepinephrine transporter  Aliases N/A N/A CLOMIPRAMINE  Aliases 169865 53.700000 PubChem-Compound ChEMBL 3H-Nisoxetine  Aliases HUMAN CLONED Millan MJ, et al., 2001
45563 Norepinephrine transporter  Aliases N/A N/A CLOMIPRAMINE  Aliases 169865 38.000000 PubChem-Compound ChEMBL 3H-Nisoxetine  Aliases HUMAN CLONED Tatsumi M, et al., 1997
Average45.85 
16778 Norepinephrine transporter  Aliases N/A N/A CLOMIPRAMINE  Aliases 169865 26.900000 PubChem-Compound ChEMBL 3H-Nisoxetine  Aliases RAT FR. CORTEX Millan MJ, et al., 2001
 


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