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The database has 60243Ki values for searching, and is growing
This list shows the Top 100 Receptors/Targets in Ki
Please let us know if you feel we should add any papers or data. We welcome all feedback/suggestions/comments
Other features on Ki DB are: Download Ki, Data Mining, CDD Interface allows mining Ki database by structure, substructure or structure similarity.
Anatomical profiling of GPCR expression is offered for selected targets.

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Your search returned 36 results:

IDReceptor/AliasesUniGeneAnat. ProfilingTest Ligand Name/AliasesNCIKi (nM)PubChemChEMBLHot Ligand/AliasesSpeciesSourceReference
47715 5-HT Transporter  Aliases NCBI - UniGene N/A DOXEPIN  Aliases N/A 201.000000 PubChem-Compound ChEMBL 3H-5-HT Uptake  Aliases RAT FR. CORTEX Cheetham SC, et.al., 1993
 
45577 5-HT Transporter  Aliases NCBI - UniGene N/A DOXEPIN  Aliases N/A 68.000000 PubChem-Compound ChEMBL 3H-IMIPRAMINE  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
4468 5-HT Transporter  Aliases NCBI - UniGene N/A DOXEPIN  Aliases N/A 126.000000 PubChem-Compound ChEMBL 3H-IMIPRAMINE  Aliases RAT BRAIN PALVIMAKI EP, ET AL., 1996
 
47693 5-HT Transporter  Aliases NCBI - UniGene N/A DOXEPIN  Aliases N/A 126.000000 PubChem-Compound ChEMBL 3H-PAROXETINE  Aliases RAT FR. CORTEX Cheetham SC, et.al., 1993
 
11617 5-HT1A  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 276.000000 PubChem-Compound ChEMBL 3H-8-OH-DPAT  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
11636 5-HT2  Aliases N/A N/A DOXEPIN  Aliases N/A 27.000000 PubChem-Compound ChEMBL 3H-KETANSERIN  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
4450 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 26.000000 PubChem-Compound ChEMBL 3H-KETANSERIN  Aliases RAT CLONED PALVIMAKI EP, ET AL., 1996
 
4432 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 8.800000 PubChem-Compound ChEMBL 3H-MESULERGINE  Aliases RAT CLONED PALVIMAKI EP, ET AL., 1996
 
4210 5-HT6  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 136.000000 PubChem-Compound ChEMBL 125I-LSD  Aliases RAT CLONED MONSMA FJ Jr. ET AL., 1993
 
11579 adrenergic Alpha1  Aliases N/A N/A DOXEPIN  Aliases N/A 23.500000 PubChem-Compound ChEMBL 3H-PRAZOSIN  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
11598 adrenergic Alpha2  Aliases N/A N/A DOXEPIN  Aliases N/A 1,270.000000 PubChem-Compound ChEMBL 3H-RAUWOLSCINE  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
62802 Alpha 1 Adrenergic Receptor  Aliases N/A N/A DOXEPIN  Aliases N/A 24.000000 PubChem-Compound ChEMBL 3H-PRAZOSIN  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
62834 Alpha 2 Adrenergic Receptor  Aliases N/A N/A DOXEPIN  Aliases N/A 1,100.000000 PubChem-Compound ChEMBL 3H-RAUWOLSCINE  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
11560 Cholinergic, muscarinic  Aliases N/A N/A DOXEPIN  Aliases N/A 23.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
35101 Cholinergic, muscarinic  Aliases N/A N/A DOXEPIN  Aliases N/A 710.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases RAT BRAIN Koe BK et al., 1983
 
41992 Cholinergic, muscarinic M1  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 38.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42011 Cholinergic, muscarinic M2  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 160.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42030 Cholinergic, muscarinic M3  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 52.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42049 Cholinergic, muscarinic M4  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 82.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42068 Cholinergic, muscarinic M5  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 75.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
62866 D2  Aliases N/A N/A DOXEPIN  Aliases N/A 2,400.000000 PubChem-Compound ChEMBL 3H-SPIROPERIDOL  Aliases HUMAN Brain caudate nucleus Richelson, Elliott et. al, 1984
 
11655 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 360.000000 PubChem-Compound ChEMBL 3H-SPIPERONE  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
45579 Dopamine Transporter  Aliases NCBI - UniGene N/A DOXEPIN  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-WIN 35,428  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
62749 H1  Aliases N/A N/A DOXEPIN  Aliases N/A 0.240000 PubChem-Compound ChEMBL 3H-doxepin  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
12001 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 0.490000 PubChem-Compound ChEMBL 3H-doxepin  Aliases HUMAN CORTICAL MEMBRANES Kanba S, et al., 1984
 
18971 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 0.320000 PubChem-Compound ChEMBL 3H-MEPYRAMINE  Aliases HUMAN CLONED Booth RG et al., 2002
47178 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 0.160000 PubChem-Compound ChEMBL 3H-MEPYRAMINE  Aliases HUMAN CLONED Ghoneim OM, et al., 2006
Average0.24 
13040 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 0.700000 PubChem-Compound ChEMBL 3H-MEPYRAMINE  Aliases RAT BRAIN Tran VT, et al., 1978
 
50414 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 0.160000 PubChem-Compound ChEMBL 3H-MEPYRAMINE  Aliases RODENT BRAIN Bucholtz E., et.al.1999
 
18946 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 0.280000 PubChem-Compound ChEMBL 3H-MEPYRAMINE  Aliases GUINEA PIG CLONED Booth RG et al., 2002
 
11541 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 0.170000 PubChem-Compound ChEMBL 3H-PYRILAMINE  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
18923 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 0.090000 PubChem-Compound ChEMBL 3H-trans-H2-PAT,(-)  Aliases HUMAN CLONED Booth RG et al., 2002
 
18959 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling DOXEPIN  Aliases N/A 0.160000 PubChem-Compound ChEMBL 3H-trans-H2-PAT,(-)  Aliases GUINEA PIG CLONED Booth RG et al., 2002
 
14423 HISTAMINE H4  Aliases NCBI - UniGene N/A DOXEPIN  Aliases N/A 105.900000 PubChem-Compound ChEMBL 3H-PYRILAMINE  Aliases HUMAN CLONED Nguyen T. et al., 2001
 
62781 Muscarinic Acetylcholine Receptor  Aliases N/A N/A DOXEPIN  Aliases N/A 80.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN Brain caudate nucleus Richelson, Elliott et. al, 1984
 
45578 Norepinephrine transporter  Aliases N/A N/A DOXEPIN  Aliases N/A 29.500000 PubChem-Compound ChEMBL 3H-Nisoxetine  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 


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