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The database has 60243Ki values for searching, and is growing
This list shows the Top 100 Receptors/Targets in Ki
Please let us know if you feel we should add any papers or data. We welcome all feedback/suggestions/comments
Other features on Ki DB are: Download Ki, Data Mining, CDD Interface allows mining Ki database by structure, substructure or structure similarity.
Anatomical profiling of GPCR expression is offered for selected targets.

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Your search returned 28 results:

IDReceptor/AliasesUniGeneAnat. ProfilingTest Ligand Name/AliasesNCIKi (nM)PubChemChEMBLHot Ligand/AliasesSpeciesSourceReference
37197 5-HT Transporter  Aliases NCBI - UniGene N/A Lofepramine  Aliases N/A 880.000000 PubChem-Compound N/A 3H-5-HT Uptake  Aliases RAT BRAIN Sanchez C, et al., 1999
 
45601 5-HT Transporter  Aliases NCBI - UniGene N/A Lofepramine  Aliases N/A 70.000000 PubChem-Compound N/A 3H-IMIPRAMINE  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
11622 5-HT1A  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 4,600.000000 PubChem-Compound N/A 3H-8-OH-DPAT  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
37230 5-HT1A  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A > 10,000.000000 PubChem-Compound N/A 3H-8-OH-DPAT  Aliases RAT CORTEX Sanchez C, et al., 1999
 
11641 5-HT2  Aliases N/A N/A Lofepramine  Aliases N/A 200.000000 PubChem-Compound N/A 3H-KETANSERIN  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
37241 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 1,200.000000 PubChem-Compound N/A 3H-KETANSERIN  Aliases RAT CORTEX Sanchez C, et al., 1999
 
11584 adrenergic Alpha1  Aliases N/A N/A Lofepramine  Aliases N/A 100.000000 PubChem-Compound N/A 3H-PRAZOSIN  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
37280 adrenergic Alpha1  Aliases N/A N/A Lofepramine  Aliases N/A 620.000000 PubChem-Compound N/A 3H-PRAZOSIN  Aliases RAT CORTEX Sanchez C, et al., 1999
 
37291 adrenergic Alpha2  Aliases N/A N/A Lofepramine  Aliases N/A 2,100.000000 PubChem-Compound N/A 3H-IDAZOXAN  Aliases RAT CORTEX Sanchez C, et al., 1999
 
11603 adrenergic Alpha2  Aliases N/A N/A Lofepramine  Aliases N/A 2,700.000000 PubChem-Compound N/A 3H-RAUWOLSCINE  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
37301 adrenergic Beta  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A > 10,000.000000 PubChem-Compound N/A 3H-DHA  Aliases RAT CORTEX Sanchez C, et al., 1999
 
11565 Cholinergic, muscarinic  Aliases N/A N/A Lofepramine  Aliases N/A 67.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
37311 Cholinergic, muscarinic  Aliases N/A N/A Lofepramine  Aliases N/A 300.000000 PubChem-Compound N/A 3H-QNB  Aliases RAT BRAIN Sanchez C, et al., 1999
 
41997 Cholinergic, muscarinic M1  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 67.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42016 Cholinergic, muscarinic M2  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 330.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42035 Cholinergic, muscarinic M3  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 130.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42054 Cholinergic, muscarinic M4  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 340.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
42073 Cholinergic, muscarinic M5  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 460.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN CLONED Stanton T, et al., 1993
 
37259 DOPAMINE D1  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 500.000000 PubChem-Compound N/A 3H-SCH23390  Aliases RAT STRIATUM Sanchez C, et al., 1999
 
11659 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 2,000.000000 PubChem-Compound N/A 3H-SPIPERONE  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
37269 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 6,700.000000 PubChem-Compound N/A 3H-SPIROPERIDOL  Aliases RAT STRIATUM Sanchez C, et al., 1999
 
37219 Dopamine Transporter  Aliases NCBI - UniGene N/A Lofepramine  Aliases N/A 3,300.000000 PubChem-Compound N/A 3H-DA UPTAKE  Aliases RAT STRIATUM Sanchez C, et al., 1999
 
45603 Dopamine Transporter  Aliases NCBI - UniGene N/A Lofepramine  Aliases N/A > 10,000.000000 PubChem-Compound N/A 3H-WIN 35,428  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
37322 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 1,000.000000 PubChem-Compound N/A 3H-MEPYRAMINE  Aliases RAT BRAIN Sanchez C, et al., 1999
 
11553 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling Lofepramine  Aliases N/A 360.000000 PubChem-Compound N/A 3H-PYRILAMINE  Aliases HUMAN BRAIN Cusack, B et al., 1993
 
37208 Norepinephrine transporter  Aliases N/A N/A Lofepramine  Aliases N/A 2.700000 PubChem-Compound N/A 3H-NE Uptake  Aliases RAT CORTEX Sanchez C, et al., 1999
 
45602 Norepinephrine transporter  Aliases N/A N/A Lofepramine  Aliases N/A 5.400000 PubChem-Compound N/A 3H-Nisoxetine  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
48365 Sigma-1  Aliases N/A N/A Lofepramine  Aliases N/A 2,520.000000 PubChem-Compound N/A 3H-Pentazocine(+)  Aliases RAT BRAIN PDSP certified data
 


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