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The database has 60243Ki values for searching, and is growing
This list shows the Top 100 Receptors/Targets in Ki
Please let us know if you feel we should add any papers or data. We welcome all feedback/suggestions/comments
Other features on Ki DB are: Download Ki, Data Mining, CDD Interface allows mining Ki database by structure, substructure or structure similarity.
Anatomical profiling of GPCR expression is offered for selected targets.

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Your search returned 22 results:

IDReceptor/AliasesUniGeneAnat. ProfilingTest Ligand Name/AliasesNCIKi (nM)PubChemChEMBLHot Ligand/AliasesSpeciesSourceReference
45604 5-HT Transporter  Aliases NCBI - UniGene N/A MAPROTILINE  Aliases N/A 5,800.000000 PubChem-Compound N/A 3H-IMIPRAMINE  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
4470 5-HT Transporter  Aliases NCBI - UniGene N/A MAPROTILINE  Aliases N/A 1,000.000000 PubChem-Compound N/A 3H-IMIPRAMINE  Aliases RAT BRAIN PALVIMAKI EP, ET AL., 1996
 
4452 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling MAPROTILINE  Aliases N/A 51.000000 PubChem-Compound N/A 3H-KETANSERIN  Aliases RAT CLONED PALVIMAKI EP, ET AL., 1996
 
4434 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling MAPROTILINE  Aliases N/A 122.000000 PubChem-Compound N/A 3H-MESULERGINE  Aliases RAT CLONED PALVIMAKI EP, ET AL., 1996
 
62811 Alpha 1 Adrenergic Receptor  Aliases N/A N/A MAPROTILINE  Aliases N/A 90.000000 PubChem-Compound N/A 3H-PRAZOSIN  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
62846 Alpha 2 Adrenergic Receptor  Aliases N/A N/A MAPROTILINE  Aliases N/A 9,400.000000 PubChem-Compound N/A 3H-RAUWOLSCINE  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
62859 D2  Aliases N/A N/A MAPROTILINE  Aliases N/A 350.000000 PubChem-Compound N/A 3H-SPIROPERIDOL  Aliases HUMAN Brain caudate nucleus Richelson, Elliott et. al, 1984
 
55114 DOPAMINE D1  Aliases NCBI - UniGene Anatomical Profiling MAPROTILINE  Aliases N/A 402.000000 PubChem-Compound N/A UNDEFINED  Aliases HUMAN UNDEFINED von Coburg Y et al., 2009
 
55142 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling MAPROTILINE  Aliases N/A 665.000000 PubChem-Compound N/A UNDEFINED  Aliases HUMAN UNDEFINED von Coburg Y et al., 2009
 
55156 DOPAMINE D3  Aliases NCBI - UniGene Anatomical Profiling MAPROTILINE  Aliases N/A 504.000000 PubChem-Compound N/A UNDEFINED  Aliases HUMAN UNDEFINED von Coburg Y et al., 2009
 
55128 DOPAMINE D5  Aliases NCBI - UniGene Anatomical Profiling MAPROTILINE  Aliases N/A 429.000000 PubChem-Compound N/A UNDEFINED  Aliases HUMAN UNDEFINED von Coburg Y et al., 2009
 
14316 Dopamine Transporter  Aliases NCBI - UniGene N/A MAPROTILINE  Aliases N/A 1,210.000000 PubChem-Compound N/A 125I-RTI-55 Binding  Aliases RAT STRIATUM Letchworth SR, et al., 2000
 
14286 Dopamine Transporter  Aliases NCBI - UniGene N/A MAPROTILINE  Aliases N/A > 10,000.000000 PubChem-Compound N/A 3H-DA UPTAKE  Aliases RAT STRIATUM Letchworth SR, et al., 2000
 
14300 Dopamine Transporter  Aliases NCBI - UniGene N/A MAPROTILINE  Aliases N/A 1,190.000000 PubChem-Compound N/A 3H-PTT Binding  Aliases RAT STRIATUM Letchworth SR, et al., 2000
 
45606 Dopamine Transporter  Aliases NCBI - UniGene N/A MAPROTILINE  Aliases N/A 1,000.000000 PubChem-Compound N/A 3H-WIN 35,428  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
62754 H1  Aliases N/A N/A MAPROTILINE  Aliases N/A 2.000000 PubChem-Compound N/A 3H-doxepin  Aliases HUMAN Brain Frontal Cortex Richelson, Elliott et. al, 1984
 
12006 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling MAPROTILINE  Aliases N/A 0.790000 PubChem-Compound N/A 3H-doxepin  Aliases HUMAN CORTICAL MEMBRANES Kanba S, et al., 1984
 
55100 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling MAPROTILINE  Aliases N/A 1.670000 PubChem-Compound N/A UNDEFINED  Aliases HUMAN UNDEFINED von Coburg Y et al., 2009
 
55086 HISTAMINE H3  Aliases NCBI - UniGene Anatomical Profiling MAPROTILINE  Aliases N/A 1,000.000000 PubChem-Compound N/A UNDEFINED  Aliases HUMAN UNDEFINED von Coburg Y et al., 2009
 
62785 Muscarinic Acetylcholine Receptor  Aliases N/A N/A MAPROTILINE  Aliases N/A 570.000000 PubChem-Compound N/A 3H-QNB  Aliases HUMAN Brain caudate nucleus Richelson, Elliott et. al, 1984
 
45605 Norepinephrine transporter  Aliases N/A N/A MAPROTILINE  Aliases N/A 11.100000 PubChem-Compound N/A 3H-Nisoxetine  Aliases HUMAN CLONED Tatsumi M, et al., 1997
 
56992 Norepinephrine transporter  Aliases NCBI - UniGene N/A MAPROTILINE  Aliases N/A 12.000000 PubChem-Compound N/A UNDEFINED  Aliases UNDEFINED UNDEFINED Heffernan GD et al., 2009
 


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