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The database has 60243Ki values for searching, and is growing
This list shows the Top 100 Receptors/Targets in Ki
Please let us know if you feel we should add any papers or data. We welcome all feedback/suggestions/comments
Other features on Ki DB are: Download Ki, Data Mining, CDD Interface allows mining Ki database by structure, substructure or structure similarity.
Anatomical profiling of GPCR expression is offered for selected targets.

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Your search returned 86 results:

IDReceptor/AliasesUniGeneAnat. ProfilingTest Ligand Name/AliasesNCIKi (nM)PubChemChEMBLHot Ligand/AliasesSpeciesSourceReference
25245 5-HT Transporter  Aliases NCBI - UniGene N/A THIOTHIXENE  Aliases N/A 3,878.000000 PubChem-Compound ChEMBL 3H-CITALOPRAM  Aliases HUMAN CLONED PDSP certified data
 
25270 5-HT1A  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 410.000000 PubChem-Compound ChEMBL 3H-8-OH-DPAT  Aliases HUMAN CLONED PDSP certified data
28626 5-HT1A  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 410.400000 PubChem-Compound ChEMBL 3H-8-OH-DPAT  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
Average410.20 
25230 5-HT1B  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 151.000000 PubChem-Compound ChEMBL 3H-GR-125743  Aliases HUMAN CLONED PDSP certified data
 
25262 5-HT1D  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 659.000000 PubChem-Compound ChEMBL 3H-GR-125743  Aliases HUMAN CLONED PDSP certified data
 
25234 5-HT1E  Aliases NCBI - UniGene N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-5HT  Aliases HUMAN CLONED PDSP certified data
 
10720 5-HT2  Aliases N/A N/A THIOTHIXENE  Aliases N/A 50.110000 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED ROTH ET AL., 1993
 
28490 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 50.000000 PubChem-Compound ChEMBL 3H-KETANSERIN  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
 
25229 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 111.000000 PubChem-Compound ChEMBL 3H-KETANSERIN  Aliases RAT CLONED PDSP certified data
 
4592 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 50.000000 PubChem-Compound ChEMBL 3H-KETANSERIN  Aliases RAT BRAIN ROTH BL, ET AL., 1992
 
4535 5-HT2A  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 50.000000 PubChem-Compound ChEMBL 3H-SPIPERONE  Aliases RAT BRAIN ROTH BL, ET AL., 1995
 
28473 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 1,400.000000 PubChem-Compound ChEMBL 125I-DOI  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
 
4565 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 1,548.000000 PubChem-Compound ChEMBL 125I-LSD  Aliases RAT CLONED ROTH BL, ET AL., 1992
 
10737 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 1,584.890000 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED ROTH ET AL., 1993
 
13950 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 1,311.000000 PubChem-Compound ChEMBL 3H-MESULERGINE  Aliases HUMAN CLONED Herrick-Davis K, et al., 2000
 
25247 5-HT2C  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 1,593.000000 PubChem-Compound ChEMBL 3H-MESULERGINE  Aliases RAT CLONED PDSP certified data
 
25244 5-HT3  Aliases NCBI - UniGene N/A THIOTHIXENE  Aliases N/A 1,863.000000 PubChem-Compound ChEMBL 3H-ZACOPRIDE  Aliases HUMAN CLONED PDSP certified data
 
25228 5-HT5a  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 361.000000 PubChem-Compound ChEMBL 3H-LSD  Aliases HUMAN CLONED PDSP certified data
 
4378 5-HT6  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 320.000000 PubChem-Compound ChEMBL 3H-LSD  Aliases HUMAN CLONED KOHEN R, ET AL., 1996
25238 5-HT6  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 208.000000 PubChem-Compound ChEMBL 3H-LSD  Aliases HUMAN CLONED PDSP certified data
28643 5-HT6  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 208.400000 PubChem-Compound ChEMBL 3H-LSD  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
Average245.47 
3110 5-HT6  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 45.000000 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED ROTH ET AL., 1993
 
25261 5-HT7  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 15.000000 PubChem-Compound ChEMBL 3H-LSD  Aliases HUMAN CLONED PDSP certified data
28660 5-HT7  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 15.500000 PubChem-Compound ChEMBL 3H-LSD  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
Average15.25 
3150 5-HT7  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 12.000000 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED ROTH ET AL., 1993
 
32145 adrenergic Alpha1  Aliases N/A N/A THIOTHIXENE  Aliases N/A 25.000000 PubChem-Compound ChEMBL 3H-WB4101  Aliases RAT FOREBRAIN Megens et al., 1986
 
25256 adrenergic Alpha1A  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 12.000000 PubChem-Compound ChEMBL 125I-HEAT  Aliases HUMAN CLONED PDSP certified data
 
28558 adrenergic Alpha1A  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 11.000000 PubChem-Compound ChEMBL 3H-PRAZOSIN  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
 
25258 adrenergic Alpha1B  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 35.000000 PubChem-Compound ChEMBL 125I-HEAT  Aliases HUMAN CLONED PDSP certified data
 
32082 adrenergic Alpha2  Aliases N/A N/A THIOTHIXENE  Aliases N/A 1,200.000000 PubChem-Compound ChEMBL 3H-CLONIDINE  Aliases RAT CORTEX Megens et al., 1986
 
32094 adrenergic Alpha2  Aliases N/A N/A THIOTHIXENE  Aliases N/A 1,400.000000 PubChem-Compound ChEMBL 3H-IDAZOXAN  Aliases RAT CORTEX Megens et al., 1986
 
25242 adrenergic Alpha2A  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 80.000000 PubChem-Compound ChEMBL 3H-CLONIDINE  Aliases HUMAN CLONED PDSP certified data
28575 adrenergic Alpha2A  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 79.900000 PubChem-Compound ChEMBL 3H-CLONIDINE  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
Average79.95 
25227 adrenergic Alpha2B  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 50.000000 PubChem-Compound ChEMBL 3H-CLONIDINE  Aliases HUMAN CLONED PDSP certified data
28592 adrenergic Alpha2B  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 50.200000 PubChem-Compound ChEMBL 3H-CLONIDINE  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
Average50.10 
25260 adrenergic Alpha2C  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 52.000000 PubChem-Compound ChEMBL 3H-CLONIDINE  Aliases HUMAN CLONED PDSP certified data
28609 adrenergic Alpha2C  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 51.900000 PubChem-Compound ChEMBL 3H-CLONIDINE  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
Average51.95 
25268 adrenergic Beta1  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 125I-Pindolol  Aliases HUMAN CLONED PDSP certified data
 
25225 adrenergic Beta2  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 125I-Pindolol  Aliases HUMAN CLONED PDSP certified data
 
25222 Calcium channel  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-Nitrendipine  Aliases RAT HEART PDSP certified data
 
25239 CANNABINOID CB1  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-CP-55940  Aliases RAT BRAIN PDSP certified data
 
25269 Cholinergic, muscarinic M1  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED PDSP certified data
 
25255 Cholinergic, muscarinic M2  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED PDSP certified data
 
25232 Cholinergic, muscarinic M3  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED PDSP certified data
28541 Cholinergic, muscarinic M3  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
 
25231 Cholinergic, muscarinic M4  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED PDSP certified data
 
25249 Cholinergic, muscarinic M5  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 5,376.000000 PubChem-Compound ChEMBL 3H-QNB  Aliases HUMAN CLONED PDSP certified data
 
25246 Cholinergic, Nicotinic Alpha1Beta2  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-Epibatidine  Aliases HUMAN CLONED PDSP certified data
 
25223 Cholinergic, Nicotinic Alpha2Beta2  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-Epibatidine  Aliases HUMAN CLONED PDSP certified data
 
25235 Cholinergic, Nicotinic Alpha2Beta4  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-Epibatidine  Aliases HUMAN CLONED PDSP certified data
 
25259 Cholinergic, Nicotinic Alpha3Beta2  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-Epibatidine  Aliases HUMAN CLONED PDSP certified data
25265 Cholinergic, Nicotinic Alpha3Beta2  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-Epibatidine  Aliases HUMAN CLONED PDSP certified data
 
25252 Cholinergic, Nicotinic Alpha7  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-Epibatidine  Aliases HUMAN CLONED PDSP certified data
 
25241 DOPAMINE D1  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 51.000000 PubChem-Compound ChEMBL 3H-SCH23390  Aliases HUMAN CLONED PDSP certified data
 
33851 DOPAMINE D1  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 1,520.000000 PubChem-Compound ChEMBL 3H-SCH23390  Aliases RAT FR. CORTEX Andersen PH, et al., 1985
 
10752 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 0.630000 PubChem-Compound ChEMBL 3H-LSD  Aliases RAT CLONED ROTH ET AL., 1993
 
25226 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 1.400000 PubChem-Compound ChEMBL 3H-NMSP  Aliases HUMAN CLONED PDSP certified data
28507 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 0.630000 PubChem-Compound ChEMBL 3H-NMSP  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
Average1.01 
4498 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 0.630000 PubChem-Compound ChEMBL 3H-SPIPERONE  Aliases RAT BRAIN ROTH BL, ET AL., 1995
 
33876 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 0.660000 PubChem-Compound ChEMBL 3H-SPIPERONE  Aliases RAT FR. CORTEX Andersen PH, et al., 1985
 
39030 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 0.200000 PubChem-Compound ChEMBL R-SAT  Aliases HUMAN CLONED Burstein ES, et al., 2005
39061 DOPAMINE D2  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 0.030000 PubChem-Compound ChEMBL R-SAT  Aliases HUMAN CLONED Burstein ES, et al., 2005
Average0.12 
25251 DOPAMINE D3  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 185.000000 PubChem-Compound ChEMBL 3H-NMSP  Aliases RAT CLONED PDSP certified data
 
39101 DOPAMINE D3  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 0.300000 PubChem-Compound ChEMBL R-SAT  Aliases HUMAN CLONED Burstein ES, et al., 2005
39131 DOPAMINE D3  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 0.500000 PubChem-Compound ChEMBL R-SAT  Aliases HUMAN CLONED Burstein ES, et al., 2005
Average0.40 
25253 DOPAMINE D4  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 203.000000 PubChem-Compound ChEMBL 3H-NMSP  Aliases HUMAN CLONED PDSP certified data
 
4496 DOPAMINE D4  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 77.000000 PubChem-Compound ChEMBL 3H-SPIPERONE  Aliases RAT CLONED ROTH BL, ET AL., 1995
 
7054 DOPAMINE D4.2  Aliases N/A N/A THIOTHIXENE  Aliases N/A 410.000000 PubChem-Compound ChEMBL 3H-NGD 94-1  Aliases HUMAN CLONED TALLMAN JF, ET AL., 1997
 
7071 DOPAMINE D4.2  Aliases N/A N/A THIOTHIXENE  Aliases N/A 685.000000 PubChem-Compound ChEMBL 3H-YM 09151-2  Aliases HUMAN CLONED TALLMAN JF, ET AL., 1997
 
25271 DOPAMINE D5  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 261.000000 PubChem-Compound ChEMBL 3H-SCH23390  Aliases HUMAN CLONED PDSP certified data
 
25263 Dopamine Transporter  Aliases NCBI - UniGene N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-GBR 12935  Aliases HUMAN CLONED PDSP certified data
 
25267 GABA A  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-MUSCIMOL  Aliases RAT FOREBRAIN PDSP certified data
 
25240 GABA A Benzodiazepine  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-RO-15-1788  Aliases RAT FOREBRAIN PDSP certified data
 
25224 GABA B  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-BACLOFEN  Aliases RAT FOREBRAIN PDSP certified data
 
25243 Glutamate-NMDA-MK801  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-MK-801  Aliases RAT FOREBRAIN PDSP certified data
25248 Glutamate-NMDA-MK801  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-MK-801  Aliases RAT FOREBRAIN PDSP certified data
 
12013 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 4.400000 PubChem-Compound ChEMBL 3H-doxepin  Aliases HUMAN CORTICAL MEMBRANES Kanba S, et al., 1984
 
25237 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 12.000000 PubChem-Compound ChEMBL 3H-PYRILAMINE  Aliases HUMAN CLONED PDSP certified data
28524 HISTAMINE H1  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 4.000000 PubChem-Compound ChEMBL 3H-PYRILAMINE  Aliases HUMAN CLONED Kroeze WK, et.al., 2003
Average8.00 
25236 HISTAMINE H2  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 411.000000 PubChem-Compound ChEMBL 3H-TIOTIDINE  Aliases HUMAN CLONED PDSP certified data
 
25264 HISTAMINE H3  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A 1,336.000000 PubChem-Compound ChEMBL 3H-Alpha-Me-histamine  Aliases GUINEA PIG CLONED PDSP certified data
 
25266 HISTAMINE H4  Aliases NCBI - UniGene N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-Histamine  Aliases HUMAN CLONED PDSP certified data
 
25233 Imidazoline I1  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 125I-Pindolol  Aliases RAT PC12 PDSP certified data
 
25254 Norepinephrine transporter  Aliases N/A N/A THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-Nisoxetine  Aliases HUMAN CLONED PDSP certified data
 
25257 Prostaglandin E3  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-PGE2  Aliases HUMAN CLONED PDSP certified data
 
25250 Prostaglandin E4  Aliases NCBI - UniGene Anatomical Profiling THIOTHIXENE  Aliases N/A > 10,000.000000 PubChem-Compound ChEMBL 3H-PGE2  Aliases HUMAN CLONED PDSP certified data
 


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